Product Datasheet
TNIK Antibody
Catalog Number: 43698
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9UKE5
NCBI Gene ID: 23043
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human TNIK
- appl_detail:
Immunohistochemistry: 1: 20-100
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total TNIK protein.
- Background:
- TNIK (TRAF2 and NCK-interacting protein kinase) is a 1,360 amino acid protein that contains one protein kinase domain and belongs to a subfamily of Ser/Thr protein kinases. Expressed ubiquitously with highest expression in brain, heart and skeletal muscle, TNIK functions as a stress-activated Ser/Thr kinase that catalyzes the ATP-dependent phosphorylation of target proteins and is thought to play a role in the response to environmental stress. Additionally, via its catalytic activity, TNIK may participate in cytoskeletal regulation events throughout the cell. TNIK exists as 8 isoforms that are produced by alternative splicing events.
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