Product Datasheet
SDC2 Antibody
Catalog Number: 43692
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P34741
NCBI Gene ID: 6383
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human SDC2
- appl_detail:
Immunohistochemistry: 1: 20-100
- other_names:
- HSPG; CD362; HSPG1; SYND2
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total SDC2 protein.
- Background:
- The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types.
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