Product Datasheet
GZMH Antibody
Catalog Number: 43676
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P20718
NCBI Gene ID: 2999
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human GZMH
- appl_detail:
- Western blotting: 1:200-1000
- other_names:
- CCP-X; CGL-2; CSP-C; CTLA1; CTSGL2
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total GZMH protein.
- Background:
- This gene encodes a member of the peptidase S1 family of serine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease. This protein is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. This gene is present in a gene cluster with another member of the granzyme subfamily on chromosome 14.
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