Product Datasheet
GNLY Antibody
Catalog Number: 43674
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P22749
NCBI Gene ID: 10578
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human GNLY
- appl_detail:
Immunohistochemistry: 1: 20-100
- other_names:
- LAG2; NKG5; LAG-2; D2S69E; TLA519
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total GNLY protein.
- Background:
- The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified.
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