Product Datasheet
TNFRSF10A Antibody
Catalog Number: 43656
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O00220
NCBI Gene ID: 8797
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human TNFRSF10A
- appl_detail:
Immunohistochemistry: 1: 20-100
- other_names:
- DR4; APO2; CD261; TRAILR1; TRAILR-1
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total TNFRSF10A protein.
- Background:
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.?
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