Product Datasheet
DEFB104A Antibody
Catalog Number: 43654
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q8WTQ1
NCBI Gene ID: 140596
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human DEFB104A
- appl_detail:
Immunohistochemistry: 1: 100-250
- other_names:
- BD-4; DEFB4; hBD-4; DEFB-4; DEFB104
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total DEFB104A protein.
- Background:
- Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 104, DEFB104A and DEFB104B, in head-to-head orientation. This gene, DEFB104A, represents the more centromeric copy.
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