Product Datasheet
SPAG4 Antibody
Catalog Number: 43626
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9NPE6
NCBI Gene ID: 6676
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human SPAG4
- appl_detail:
- Western blotting: 1:200-1000
Immunohistochemistry: 1: 100-300
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total SPAG4 protein.
- Background:
- The mammalian sperm flagellum contains two cytoskeletal structures associated with the axoneme: the outer dense fibers surrounding the axoneme in the midpiece and principal piece and the fibrous sheath surrounding the outer dense fibers in the principal piece of the tail. Defects in these structures are associated with abnormal tail morphology, reduced sperm motility, and infertility. In the rat, the protein encoded by this gene associates with an outer dense fiber protein via a leucine zipper motif and localizes to the microtubules of the manchette and axoneme during sperm tail development.
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