Product Datasheet
ZFP36 Antibody
Catalog Number: 43567
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P26651
NCBI Gene ID: 7538
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human ZFP36
- appl_detail:
Immunohistochemistry: 1: 100-200
- other_names:
- TTP; G0S24; GOS24; TIS11; NUP475; zfp-36; RNF162A
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total ZFP36 protein.
- Background:
- mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Recruits deadenylase CNOT7 (and probably the CCR4-NOT complex) via association with CNOT1. Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF). Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF).
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