Product Datasheet
LASP1 Antibody
Catalog Number: 43565
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q14847
NCBI Gene ID: 3927
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein
- appl_detail:
- Western blotting: 1:200-1000
Immunohistochemistry: 1: 20-100
- other_names:
- MLN50; Lasp-1
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total LASP1 protein.
- Background:
- This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer.
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