Product Datasheet
ABHD14B Antibody
Catalog Number: 43552
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q96IU4
NCBI Gene ID: 84836
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein
- appl_detail:
- Western blotting: 1:200-1000
- other_names:
- CIB; HEL-S-299
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total ABHD14B protein.
- Background:
- The Ab hydrolase domain containing (ABHD) gene subfamily is comprised of 15 mostly uncharacterized members. Most of which utilize a serine nucleophile to form the G-X-S-X-G nucleophile elbow. ABHD1 plays a role in metabolizing smoking xenobiotics. ABHD2 participates in the development of atherosclerosis. ABHD4 is involved in an alternative synthesis pathway of NAE. Mutations in ABHD5 contribute to Chanarin-Dorfman syndrome. ABDH6 may play a role in nervous system metabolism and signaling. ABHD14B is a 210 amino acid protein that localizes to both the cytoplasm and the nucleus where it exists as two alternatively spliced isoforms.
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