Product Datasheet
RASSF8 Antibody
Catalog Number: 43530
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q8NHQ8
NCBI Gene ID: 11228
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human RASSF8
- appl_detail:
Immunohistochemistry: 1: 100-250
- other_names:
- HOJ1; C12orf2
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total RASSF8 protein.
- Background:
- This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.?
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