Product Datasheet  
KBTBD8 antibody  
Catalog Number: 43486  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q86T82
    NCBI Protein#: BC117487
  • Form of Antibody：  
  • pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Fusion protein of human KBTBD8
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  
  • WB dilution:1:1000-1:5000
    IHC dilution:1:50-1:300
  • other_names：  
  • TAKRP; TA-KRP
  • Purification：  
  • Antigen affinity purification
  • Specificity：  
  • Applications：  
  • WB, IHC
  • Background：  
  • Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of neural crest specification. The BCR(KBTBD8) complex acts by mediating monoubiquitination of NOLC1 and TCOF1: monoubiquitination promotes the formation of a NOLC1-TCOF1 complex that acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification.



 
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