Product Datasheet
NUDT5 Antibody
Catalog Number: 43474
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9UKK9
Gene ID: 11164
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human NUDT5
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- YSA1; YSA1H; YSAH1; hYSAH1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total NUDT5 protein.
- Background:
- This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA.
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