Product Datasheet
E2F3 Antibody
Catalog Number: 43472
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O00716
Gene ID: 1871
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human E2F3
- appl_detail:
- Western blotting: 1:200-1:1000
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total E2F3 protein.
- Background:
- This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants.
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