Product Datasheet
E2F1 Antibody
Catalog Number: 43456
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q01094
Gene ID: 1869
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human E2F1
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- RBP3; E2F-1; RBAP1; RBBP3
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total E2F1 protein.
- Background:
- The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain.
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