Product Datasheet
NFKBIZ Antibody
Catalog Number: 43416
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9BYH8
Gene ID: 64332
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human NFKBIZ
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- IKBZ; INAP; MAIL
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total NFKBIZ protein.
- Background:
- This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production.?
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