Product Datasheet
KL Antibody
Catalog Number: 43404
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9UEF7
Gene ID: 9365
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human KL
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- KLOT; Klotho; Klotho peptide
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total KL protein.
- Background:
- This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss.
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