Product Datasheet
DAND5 Antibody
Catalog Number: 43367
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q8N2K1
Gene ID: 118424
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein of human DAND5
- other_names:
- NCUBE2; NCUBE-2; PRO2121
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total DAND5 protein.
- Background:
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins.
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