Product Datasheet
WRAP53 Antibody
Catalog Number: 43348
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9BUR4
Gene ID: 55135
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human WRAP53
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:10-1:50
- other_names:
- DKCB3; TCAB1; WDR79
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total WRAP53 protein.
- Background:
- This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs.?
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