Product Datasheet
TSC22D1 Antibody
Catalog Number: 43344
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q15714
Gene ID: 8848
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein of human TSC22D1
- appl_detail:
Immunohistochemistry: 1:25-1:100
- other_names:
- Ptg-2; TSC22; TGFB1I4
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TSC22D1 protein.
- Background:
- This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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