Product Datasheet
NOS1 Antibody
Catalog Number: 43310
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P29475
Gene ID: 4842
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human NOS1
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:30-1:150
- other_names:
- NOS; bNOS; nNOS; IHPS1; N-NOS; NC-NOS
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total NOS1 protein.
- Background:
- The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection.
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