Product Datasheet
DRD3 Antibody
Catalog Number: 43293
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P35462
Gene ID: 1814
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human DRD3
- appl_detail:
Immunohistochemistry: 1:25-1:100
- other_names:
- D3DR; ETM1; FET1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total DRD3 protein.
- Background:
- This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).
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