Product Datasheet
TRPV6 Antibody
Catalog Number: 43287
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9H1D0
Gene ID: 55503
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human TRPV6
- appl_detail:
Immunohistochemistry: 1:25-1:100
- other_names:
- CAT1; CATL; ZFAB; ECAC2; ABP/ZF; LP6728; HSA277909
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TRPV6 protein.
- Background:
- This gene encodes a member of a family of multipass membrane proteins that functions as calcium channels. The encoded protein contains N-terminal ankyrin repeats, which are required for channel assembly and regulation. Translation initiation for this protein occurs at a non-AUG start codon that is decoded as methionine. This gene is situated next to a closely related gene for transient receptor potential cation channel subfamily V member 5 (TRPV5). This locus has experienced positive selection in non-African populations, resulting in several non-synonymous codon differences among individuals of different genetic backgrounds.?
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