Product Datasheet
BMF Antibody
Catalog Number: 43281
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q96LC9
Gene ID: 90427
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human BMF
- other_names:
- Bcl-2-modifying factor; Bcl2 modifying factor; BMF; FLJ00065
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total BMF protein.
- Background:
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis.
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