Product Datasheet
ATG16L1 Antibody
Catalog Number: 43247
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q676U5
Gene ID: 55054
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human ATG16L1
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
- other_names:
- IBD10; WDR30; APG16L; ATG16A; ATG16L
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ATG16L1 protein.
- Background:
- The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.
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