Product Datasheet
ACVRL1 Antibody
Catalog Number: 43246
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P37023?
Gene ID: 94
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human ACVRL1
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
- other_names:
- HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ACVRL1 protein.
- Background:
- This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases.?
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