Product Datasheet
COL8A2 Antibody
Catalog Number: 43219
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P25067
Gene ID: 1296
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human COL8A2
- appl_detail:
Immunohistochemistry: 1:25-1:100
- other_names:
- FECD; PPCD; FECD1; PPCD2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total COL8A2 protein.
- Background:
- This gene encodes the alpha 2 chain of type VIII collagen. This protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2. Alternative splicing results in multiple transcript variants.?
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