Product Datasheet
AICDA Antibody
Catalog Number: 43199
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9GZX7
Gene ID: 57379
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human AICDA
- appl_detail:
Immunohistochemistry: 1:25-1:100
- other_names:
- AID; ARP2; CDA2; HIGM2; HEL-S-284
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total AICDA protein.
- Background:
- This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).
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