Product Datasheet
CD70 Antibody
Catalog Number: 43184
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P32970
Gene ID: 970
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human CD70
- appl_detail:
Immunohistochemistry: 1:40-1:250
- other_names:
- CD27L; CD27LG; TNFSF7
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CD70 protein.
- Background:
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
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