Product Datasheet
WNK1 Antibody
Catalog Number: 43183
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9H4A3
Gene ID: 65125
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human WNK1
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:30-1:150
- other_names:
- KDP; PSK; p65; HSN2; HSAN2; PRKWNK1; PPP1R167
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total WNK1 protein.
- Background:
- This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.
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