Product Datasheet
TPD52 Antibody
Catalog Number: 43166
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P55327
Gene ID: 7163
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human TPD52
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
- other_names:
- D52; N8L; PC-1; PrLZ; hD52
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TPD52 protein.
- Background:
- The tumor protein D52 (TPD52) family consists of three members, TPD52, TPD52L1 (D53), and TPD52L2 (D54). These small coiled-coil motif bearing proteins interact in hetero- and homomeric fashion. The TPD52 gene maps to chromosome 8q21, and due to amplification, shows frequent overexpression in prostate and breast carcinomas. TPD52 bound to annexin VI in a Ca(2+)-dependent manner, suggesting that these molecules may act in concert to regulate secretory processes in plasma cells.
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