Product Datasheet
TNFSF15 Antibody
Catalog Number: 43164
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O95150
Gene ID: 9966
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human TNFSF15
- appl_detail:
Immunohistochemistry: 1:25-1:100
- other_names:
- TL1; TL1A; VEGI; VEGI192A
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TNFSF15 protein.
- Background:
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells.?
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