Product Datasheet
MACC1 Antibody
Catalog Number: 43136
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q6ZN28
Gene ID: 346389
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human MACC1
- appl_detail:
Immunohistochemistry: 1:25-1:100
- other_names:
- 7A5; SH3BP4L
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MACC1 protein.
- Background:
- MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival?
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