Product Datasheet
LOXL2 Antibody
Catalog Number: 43135
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9Y4K0
Gene ID: 4017
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human LOXL2
- appl_detail:
Immunohistochemistry: 1:20-1:100
- other_names:
- LOR2; WS9-14
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total LOXL2 protein.
- Background:
- This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
© Signalway Biotechnology All Rights Reserved.