Product Datasheet
DNASE2 Antibody
Catalog Number: 43130
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O00115
Gene ID: 1777
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human DNASE2
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:30-1:150
- other_names:
- DNL; DNL2; DNASE2A
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total DNASE2 protein.
- Background:
- This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record.
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