Product Datasheet
HTRA1 Antibody
Catalog Number: 43120
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q92743
Gene ID: 5654
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human HTRA1
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
- other_names:
- L56; HtrA; ARMD7; ORF480; PRSS11; CARASIL
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total HTRA1 protein.
- Background:
- This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7.
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