Product Datasheet
LRP8 Antibody
Catalog Number: 43118
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q14114
Gene ID: 7804
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human LRP8
- appl_detail:
Immunohistochemistry: 1:25-1:100
- other_names:
- MCI1; LRP-8; APOER2; HSZ75190
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total LRP8 protein.
- Background:
- This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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