Product Datasheet
ADAMTS13 Antibody
Catalog Number: 43116
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q76LX8
Gene ID: 11093
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human ADAMTS13
- appl_detail:
Immunohistochemistry: 1:25-1:100
- other_names:
- VWFCP; C9orf8; vWF-CP; ADAM-TS13; ADAMTS-13
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ADAMTS13 protein.
- Background:
- This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants.
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