Product Datasheet
XAF1 Antibody
Catalog Number: 43649
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q6GPH4
NCBI Gene ID: 54739
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human XAF1
- appl_detail:
Immunohistochemistry: 1: 10-50
- other_names:
- BIRC4BP; XIAPAF1; HSXIAPAF1
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total XAF1 protein.
- Background:
- This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene.?
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