Product Datasheet
MLXIPL Antibody
Catalog Number: 43648
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9NP71
NCBI Gene ID: 51085
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human MLXIPL
- appl_detail:
Immunohistochemistry: 1: 20-100
- other_names:
- MIO; CHREBP; MONDOB; WBSCR14; WS-bHLH; bHLHd14
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total MLXIPL protein.
- Background:
- This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants.?
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