Product Datasheet
MASP2 Antibody
Catalog Number: 43097
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O00187
Gene ID: 10747
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human MASP2
- appl_detail:
Immunohistochemistry: 1:25-1:100
- other_names:
- sMAP; MAP19; MASP-2; MASP1P1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MASP2 protein.
- Background:
- The Ra-reactive factor (RARF) is a complement-dependent bactericidal factor that binds to the Ra and R2 polysaccharides expressed by certain enterobacteria. Alternate splicing of this gene results in two transcript variants encoding two RARF components that are involved in the mannan-binding lectin pathway of complement activation. The longer isoform is cleaved into two chains which form a heterodimer linked by a disulfide bond. The encoded proteins are members of the trypsin family of peptidases.
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