Product Datasheet
HAO1 Antibody
Catalog Number: 43063
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9UJM8
Gene ID: 54363
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human HAO1
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
- other_names:
- GOX; GOX1; HAOX1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total HAO1 protein.
- Background:
- This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site.
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