Product Datasheet  
DECR2 Antibody  
Catalog Number: 42998  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q9NUI1
    Gene ID: 26063
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein of human DECR2
  • reactivity：  
  • Hu
  • appl_detail：  

  • Immunohistochemistry: 1:25-1:100
  • other_names：  
  • PDCR; SDR17C1
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total DECR2 protein.
  • Applications：  
  • IHC
  • Background：  
  • DECR2 (2,4-dienoyl-CoA reductase 2), also known as PDCR (peroxisomal 2,4-dienoyl-CoA reductase) or SDR17C1, is a 292 amino acid member of the short-chain dehydrogenases/reductases (SDR) protein family and the 2,4-dienoyl-CoA reductase protein subfamily. Localized to the peroxisome, DECR2 is an auxiliary enzyme of beta-oxidation that catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. DECR2 has also been shown to have catalytic activity towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA and short and medium chain 2,4-dienoyl-CoAs, suggesting that DECR2 is not a rate limiting step in the degradation of docosahexaenoic acid in the peroxisome. DECR2 is expressed as three isoforms produced by alternative splicing events.



 
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