Product Datasheet
KHDRBS3 Antibody
Catalog Number: 42967
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O75525
Gene ID: 10656
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein of human KHDRBS3
- appl_detail:
Immunohistochemistry: 1:25-1:100
- other_names:
- Etle; SALP; SLM2; SLM-2; TSTAR; T-STAR; etoile
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total KHDRBS3 protein.
- Background:
- RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. May play a role as a negative regulator of cell growth. Inhibits cell proliferation. Involved in splice site selection of vascular endothelial growth factor. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. Involved in post-transcriptional regulation of HIV-1 gene expression. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro.
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