Product Datasheet
PHTF2 Antibody
Catalog Number: 42907
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q8N3S3
Gene ID: 57157
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human PHTF2
- appl_detail:
-
Immunohistochemistry: 1:100-1:200
- other_names:
- DKFZp564F013; FLJ33324; MGC86999; PHTF2; Putative homeodomain transcription factor 2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PHTF2 protein.
- Background:
- PHTF2 (putative homeodomain transcription factor 2) is a 785 amino acid protein that contains one basic helix-loop-helix (bHLH) domain and belongs to the PHTF family. Homologous to PHTF1, PHTF2 exhibits strongest similarity within putative homeodomains and both N- and C-terminal regions. Existing as four alternatively spliced isoforms, PHTF2 localizes to nucleus and participates in DNA binding. PHTF2 may also play a role in transcriptional regulation. While PHTF1 is expressed mainly in testis, PHTF2 is predominantly expressed in muscle, which suggests that both may have acquired different functions after their duplication and divergence. The gene that encodes PHTF2 maps to human chromosome 7q11.23.
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