Product Datasheet
RIMKLB Antibody
Catalog Number: 42904
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9ULI2
Gene ID: 57494
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein of human RIMKLB
- appl_detail:
Immunohistochemistry: 1:25-1:100
- other_names:
- NAAGS; FAM80B; NAAGS-I
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total RIMKLB protein.
- Background:
- RIMKLB (ribosomal modification protein rimK-like family member B), also known as NAAGS (N-acetyl-aspartyl-glutamate synthetase B), beta-citryl-glutamate synthase B or FAM80B, is a 386 amino acid cytoplasmic protein that belongs to the rimK family. Acting as the catalyst in the synthesis of beta-citryl-glutamate and N-acetyl-aspartyl-glutamate, RIMKLB contains one ATP-grasp domain and exists as two alternatively spliced isoforms. The gene encoding RIMKLB maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
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