Product Datasheet  
ZFAND1 Antibody  
Catalog Number: 42869  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q8TCF1
    Gene ID: 79752
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Full length fusion protein of human ZFAND1
  • reactivity：  
  • Hu
  • appl_detail：  

  • Immunohistochemistry: 1:30-1:150
  • other_names：  
  • AN1-type zinc finger protein 1; FLJ14007; ZFAN1; ZFAND1; zinc finger, AN1-type domain 1
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total ZFAND1 protein.
  • Applications：  
  • IHC
  • Background：  
  • Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr¨¹ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZFAND1 (AN1-type zinc finger protein 1) is a 268 amino acid protein that contains 2 AN1-type zinc fingers, which are often found in proteins that contain a ubiquitin-like domain and therefore play a role in the ubiquitination pathway. AN1-type zinc fingers contains six conserved cysteines and two histidines and have a dimetal (zinc)-bound alpha/beta fold. There are two isoforms of ZFAND1 that are produced as a result of alternative splicing events.



 
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