Product Datasheet
SWAP70 Antibody
Catalog Number: 42812
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9UH65
Gene ID: 23075
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human SWAP70
- appl_detail:
Immunohistochemistry: 1:25-1:100
- other_names:
- HSPC321; SWAP-70
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SWAP70 protein.
- Background:
- Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity).
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