Product Datasheet
SDCBP Antibody
Catalog Number: 42808
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O00560
Gene ID: 6386
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein of human SDCBP
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
- other_names:
- ST1; MDA9; SYCL; MDA-9; TACIP18
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SDCBP protein.
- Background:
- The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus.?
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