Product Datasheet
ITGA5 Antibody
Catalog Number: 42807
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P08648
Gene ID: 3678
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human ITGA5
- appl_detail:
Immunohistochemistry: 1:25-1:100
- other_names:
- FNRA; CD49e; VLA-5; VLA5A
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ITGA5 protein.
- Background:
- The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. Integrin alpha 5 and integrin alpha V chains are produced by distinct genes.
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